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Fungal Diseases in Cats

Fungi are a large family that includes mushrooms. They live in soil and organic material. Many types of fungi spread via airborne spores. Fungus spores, which resist heat and can live for long periods without water, gain entrance to the body through the respiratory tract or a break in the skin.

Fungal diseases can be divided into two categories. The first are fungi that affect only the skin or mucous membranes, such as ringworm and thrush. In the second category, the fungus is widespread and involves the liver, lungs, brain, and other organs, in which case the disease is systemic.

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Systemic diseases are caused by fungi that live in soil and organic material. Spores, which resist heat and can live for long periods without water, gain entrance through the respiratory system or through the skin at the site of a puncture. Systemic fungal diseases tend to occur in chronically ill or poorly nourished cats.

Fungal diseases are difficult to recognize and treat. X-rays, biopsies, fungal cultures, and serologic blood tests are used to make a diagnosis. Suspect a fungus when an unexplained infection fails to respond to a full course of antibiotics. Although many systemic fungal agents can both infect humans and cats, only Sporotrichosis has been shown to infect humans following direct exposure to infected cats.


This disease, caused by the yeastlike fungus Cryptococcus neoformans, is the most common systemic fungal infection of cats. It tends to occur in young adult animals. It is acquired by inhaling spores found in soil heavily contaminated by bird droppings, especially those of pigeons. The likelihood of infection is increased if the cat has an immune deficiency. However, not all cats who develop cryptococcosis are immune depressed.

Nasal cryptococcosis occurs in 50 percent of cases. Signs include sneezing, snuffling, a mucoid to bloody discharge from one or both nostrils, coughing, and obstructed breathing. Flesh-colored polyplike growths may protrude from the nose. The infection may extend to the brain and cause fatal meningitis with neurological signs such as circling and seizures. Ocular damage, including blindness, may also be noted.

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